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RUAN, KE-HE
One or more keywords matched the following items that are connected to RUAN, KE-HE
Item TypeName
Academic Article Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents.
Academic Article Determination of the membrane contact residues and solution structure of the helix F/G loop of prostaglandin I2 synthase.
Academic Article Primary structure of human thromboxane synthase determined from the cDNA sequence.
Academic Article New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators.
Academic Article Substrate access channel topology in membrane-bound prostacyclin synthase.
Academic Article The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase.
Academic Article Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin.
Academic Article Solution structure of a common substrate mimetic of cyclooxygenase-downstream synthases bound to an engineered thromboxane A2 synthase using a high-resolution NMR technique.
Academic Article Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin.
Academic Article An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector.
Academic Article Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase.
Academic Article Advance in understanding the biosynthesis of prostacyclin and thromboxane A2 in the endoplasmic reticulum membrane via the cyclooxygenase pathway.
Academic Article From the design to the clinical application of thromboxane modulators.
Academic Article COX-2-10aa-PGIS gene therapy improves erectile function in rats after cavernous nerve injury.
Concept Thromboxane-A Synthase
Concept Nitric Oxide Synthase Type III
Academic Article A novel single-chain enzyme complex with chain reaction properties rapidly producing thromboxane A2 and exhibiting powerful anti-bleeding functions.
Academic Article Engineering 'Enzymelink' for screening lead compounds to inhibit mPGES-1 while maintaining prostacyclin synthase activity.
Academic Article Latest progress in the development of cyclooxygenase-2 pathway inhibitors targeting microsomal prostaglandin E2 synthase-1.
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  • Glycogen Synthase